ABSTRACT
There is considerable significance for partial genetical overlap between schizophrenia and bipolar disordersbased on family and twin studies. Though the two disorders are treated differently by their diagnosticcategories, recent evidence supports that they are more closely associated. Inspite of considerable overlapin epidemiologic features, there is no specification of the risk factors. Moreover, a significant overlap in thegenes contributing to schizophrenia and bipolar disorder has been revealed by family and twin studies.Keeping all these in view, the findings in various studies from the worldwide are reviewed after a carefulresearch of articles published in Indian journal of psychiatry, Libigenesis, Scihub and Pubmed
ABSTRACT
Chromosomal analysis was performed in a series of 30 women with repeated spontaneous abortions and their husbands. Out of the 30 women, one woman of age 28 years with history of spontaneous abortions was detected to be a chromosomal mosaic 46,XX/47,XXX and with corresponding sex chromatin positive picture C +ve / ++ve. She had normal phenotype and spontaneous abortions that occurred in the second/third months of pregnancy. Her husband was normal and has normal karyotype (46,XY).
ABSTRACT
Values of serium Tri ido Thyronine (T3), Thyroxine (T4) thyroid stimulating hormone (TSH) Follicle stimulating hormones (FSH) are established in 70 primary amenorrhea cases. In chromosomally abnormal cases, the follicle stimulating values are elevated and it is further interesting to note that all these cases have mossaicism 45,X/46,XX. In 4 chromosomally abnormal cases Tri ido thyronine (T3), thyroxine (T4) and thyroid stimulating hormone (TSH) have shown abnormal values. Out of these 4 cases, 2 cases were with 45,X and 2 cases with 45,X/46,XX chromosome complement. All these cases have gonadal dysgenesis, with short stature and underweight.